Improvement of diagnostics of pathologies of the nervous system, digitalization of pathomorphological and molecular-genetic studies for the implementation of personalized medicine in the Republic of Kazakhstan;
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Creation
Creation of a centralized (unified) biobank of pathologies of the nervous system for conducting scientific research aimed at developing neuroscience, improving the quality and increasing life expectancy of neurosurgical patients in the Republic of Kazakhstan.
Program objectives
It is planned to implement the following tasks in order to achieve the goal:
Automation of immunohistochemical studies and molecular genetic tumors of the central nervous system.
Introduction of digital technologies to improve the procedure for examining histological materials.
Study of the influence of environmental, climatic, genetic factors on the health of neurosurgical patients in the Republic of Kazakhstan
Formation of new directions for scientific research in the laboratory of neurosciences aimed at improving the quality and increasing the life expectancy of neurosurgical patients in the Republic of Kazakhstan.
Development of an improved depersonalized database of clinical, pathohistological, molecular genetic, neuroimaging data of neurosurgical patients who have agreed to store their biological samples and data in the biobank.
Development of standard operating procedures for collection, storage, use and quality control of biological samples as a part of the creation of a biobank of pathologies of the nervous system.
Research of new biomarkers of pathologies of the nervous system in order to create an expanded diagnostic panel of brain tumors.
Development of a program for molecular cytogenetic studies and creation of a biobank of tumors of the central nervous system.